I messed with the missile guy a bit and he can work (especially combined with lots of freezing). I just feel that the roles plasma and missile fulfill are so similar (although not exactly the same) but plasma is so much better.
Similar to that i feel like laser competes against sniper and at least in my experience, sniper seems more useful.
I’d be curious about your general go to party configuration. I realize that this changes by a tower or two depending on the map but just a general squad. For me at least I basically take cryo and plasma to every map except for when i was specifically messing with missile.
I do think if they allowed 5 tower picks, i would use the other towers a lot more.
Maybe i will save up a bunch of money and check out a fire setup (flame thrower instead of cryo, burning lasers).