There’s also no real penalty to not building a perfectly efficient deck. If you just want to play through the story, change the difficulty to Easy.
More importantly, unlike other AH games, you don’t just lose in the card game very often. You may not get the “optimal” ending and you may have done permanent damage to your character, but the story carries on.
EDIT: anyway, I’d argue that building a perfectly min/maxed and efficient deck isn’t really in the spirit of an AH game. You’re supposed to be a flawed and ultimately probably doomed character fighting impossibly powerful cosmic forces. Always having the appropriate answer to every problem right at your fingertips isn’t really very true to the theme.