I just did this build. Z-170-A, I-7 6700K, 32GB RAM.
I was delayed because I forgot to order a CPU cooler ! I ended up going with the Noctua NH-U12S and it was a sweet install. I like that you can orient the fins in two orientations, and the fan is mountable to either side, so it really gives you a lot of options.
Do make sure you register your account with microsoft - it makes an upgrade so much easier. I wasn't nagged at all.
Overall really impressed with how clean this came up. The new EFI bios lets you choose any drive as the boot drive, so that was also nice. I didn't install any of the utilities. I figure if I need them I can always go back & do them. Any of these Asus utilities worth having around?