My endgame loadout was +10 Wing of Astel and +10 Moonveil in my right hand, and +10 Carian Regal Scepter and +25 Frost Uchigatana in my left hand.
Powerstancing the two katanas gives me more raw damage output, frost and bleed when needed, but the WOA and the staff was a great set for general exploration. Plus, the final phase of the last boss in the game is very vulnerable to WOA and I cleared that phase in less than a minute with just WOA.