I'm enjoying it so far.
As usual, though I want more hotkeys! Is there a hotkey for "select next ship" or "select next system", for example? A hotkey for "select home system"? And I'd really like a hotkey for "left mouseclick" and "right mouseclick." I can get that with Autohotkeys, but in full-screen mode, ES2 doesn't always recognize autohotkey key presses, and switching to windowed full screen messes up my screen resolution. Maybe I'll try mousekeys.
I know most people don't care, but I need to minimize moving and clicking the mouse to preserve my aging hands. For whatever reason, key-presses bother me a lot less than mouse move/clicking.