I can see it working similar to his to return to Han Solo where he sort of hands over to a new crop to have adventures but I’m not convinced he’s quite got the physicality to be the central character again.
I thought John Williams had retired with the last Star Wars movie. With him and Fleabag returning (would it be too much to ask that she also contributes to the script?) Indy 5 might be more than the collection of geriatric jokes we’ve been enjoying for the last twelve years.
I don’t see how PWB’s presence is going to help things much other than perhaps some amusing line readings on her part. Crystal Skull had some terrific actors in it (John Hurt, Cate Blanchett), for all the good it did.
It would be pretty funny if she just kept breaking the fourth wall and smirking, Fleabag-style, though.