I just completed my third run-through of the base campaign. I played with different heroes each time and currently have 12 of my 34 unlocked heroes leveled up to 40~58. I played through the campaign once on Friendly and twice through on Mighty (and did lots of rifts with my first two teams so far), but except for damage output and sponginess of enemies, I can’t tell the difference as far as experience, money, or loot awards are concerned.
I’ve been unlocking various heroes to figure out the which ones I like best for an eventual Superior run. Hopefully, Superior difficulty will have better ISO loot. Currently I’m dropping basic ISOs in hero slots but I haven’t yet had to upgrade or craft any at all in order to succeed just yet.
Right now my teams are composed with the exact same strategy in mind: One hero that excels at Stagger, one hero that excels at single target damage output, and two other random heroes that are around the same level as the first two. I haven’t had a reason to change this up just yet, but figure that will be more important as I tackle higher level rifts in the future.
The heroes I’ve played so far:
Drax 58 (Mained)
Captain America 48 (Mained)
Luke Cage 42
Ms. Marvel 41
Captain Marvel 40 (Mained)
Iron Man 40
I’ve had no early biases or preferences for certain heroes (Except for Blade, all my favorites are DC anyway), and only selected these guys because the first team was the default (except I swapped out Groot), and all the others were the lowest available levels when I selected them (6 or 7). After I level up all the tiny guys I can work on the ones that start off at higher levels.
My favorite campaign map so far is the Black Panther map, with the jungles and tomb. It has my favorite enemies, and except for the laser-cat run, it has the fewest annoying ground obstacles (like mazes, traps, or ooze geysers etc). I also like the enemy composition and densities here. Those snipers can pack quite a punch if you don’t take care of them, and the area denial guys make certain battles iffy.
As for rifts, my favorites are the Rush/Wave trials, with my least favorite being boss fights. I don’t enjoy scripted boss fights in most games, so there’s nothing new there.