First win! 4 hours of careful play.
Basically got Edit Wands Anywhere as the first perk, which allowed for a snowball. Second had the Perk Lottery, which then allowed pickup of explosion/toxic/melee/electricity immunity.
Ended up with these three carrying the day.
That first was a railgun of lightning explosions, but super dangerous until immunity which was picked up late. The basic pattern was carried through a few wands. Second was explosions, and the third was even more explosions. Also had another wand filled with concentrated light (laser?) that basically was a super machine gun.