I don’t think RimWorld by itself is going to cause anyone to see other genders differently, just as I don’t think Call of Duty by itself is going to make someone a jingoistic killer.
I do however believe the cumulative effect of all media on someone can influence their thinking. If someone consumes a steady diet of HOORAH! KILL 'EM ALL! then yes, I do think that eventually they will think guns are pretty good solution to a majority of problems. So, yes, I pay attention to that kind of argument.
Again, if someone wants to make a game that has porn in it, then good for them. If someone wants to make a game with antiquated sexual ideas, then be my guest. If someone wants to make a serial killer game, well I’m sure there’s an audience for that too.
But also, all art is fair game for criticism, and that includes deep dives into the mechanics of a videogame.