Transmet was really ahead of its time when it was written; or perhaps it was a definitely product of it times and the world just sort of fell into the speculative fiction it created. Either way, it’s really good stuff that has to be read all the way through to fully appreciate what it’s doing.
I’ll second the following TPBs. Fables, Y -the Last Man, Lucifer, (even as a 2nd rate Sandman), The Losers, and the essential comic for the literary fag, Sandman.
Adding.
Promethea
It’s either an indulgence in hermetic Qabbalah theories, a dense deconstruction of the Wonder Woman stories or a surreal journey into the history of mythology. With Alan Moore, it’s probably all of them. Mainly though, the art is fantastic, with J.H. Williams trying every possible combination of panels and pagination just to get that feel.
We3
Imagine Homeward Bound meets the Terminator. Grant Morrison tends to really go out there with his concepts, (seaguy?) yet this particular story is touching, manic, violent and surprisingly grounded in almost all the right places. Again, fantastic art from Quitely.
The Defenders
You have to admire Keith Giffen for actually writing a story about Hulk, Dr Strange, Namor and the tired old trope of Demonic invasion and making it funny. Then again, Keith is a really funny writer. In the same vein, check out his TPBs of "Formerly known as the Justice League "
Lone wolf and Cub
The original Lone Samurai epic. This is a masterpiece of samurai fiction and few have ever come close to the stark portrayal of revenge and swordplay. Sure most other Manga are more fun, (Samurai Champloo for one), but Lone Wolf and Cub is almost meditative in its quality.
Batman - The Long Halloween and Dark Victory
Since the next Batman movie is heavily influenced by the Long Halloween, it’ll probably be a good idea to read it before playing a game of spot the influence in the movie. There should be a separate category for really good Batman trades too, btw.
I realize all these are kinda old Trades. I’m not sure what’s out now that really good. Personally though, I’m not a big fan of DMZ. Brian Wood took a fantastic concept and threw in so much angry rebellious angst that I’m afraid the book might shoot itself.