You know, I wish them well, but there have been a LOT of attempts to make a "good guy" organization or syndicate made up of (or dedicated against) characters from Gothic Horror stories, and the vast, vast, VAST majority of them have failed utterly. There was the recent Frankenstein movie, Jackman's Van Helsing, and the Brothers Grimm movie from a few years back.
Comics have had a better run, but not as good as you might think. Moore's League of Extraordinary Gentlemen was fantastic... but only the first run; the later attempts never managed to capture the magic. The Creature Commandos are far better in retrospect than they were in reality. More recently, I think DC tried a "Frankenstein: Agent of [Something]" which was spectacularly terrible.
I hold out hope for this movie, but only because Cruise is attached to it and he has a nose for good scripts.