I’m getting incrementally better at this game, and have made some observations which are probably obvious to better players than me, but you really have to pay attention to each Age’s deck and what’s cards are left in it. Thankfully, this is easy by just hitting a button, and the game tells you where every card from that Age is. I hosed the AI in one game by grabbing Scientific Method from the very expensive part of the track early in Age II while the other one was in one of the “about to be discarded” slots, and the AI still had Age A labs. That left him stuck with terrible research for an entire Age, and Computers came out pretty late in Age III, so my advantage lasted even longer. You really can’t afford any bottlenecks for too long, so it can be very helpful to force your opponent into one if you can.
On the other hand, the game can turn very quickly: I started a War Over Culture in Age III with a 65-45 military advantage, and Winston Churchill kicked my butt by making it 85-65 in one turn with some shenanigans I’m still studying with some skepticism. The game has some very investing rhythms in how you leapfrog technologies and such. I really like it.