Finished it after about 37 hours. Excellent game. I was level 28 at the end without killing anyone, and it was certainly a challenge. Street enemies were level 32-35, and a group of 35s of the right type could be a big challenge.
I was reluctant to rest at times because I didn’t want everyone to get sick again and then I’d have to run all over the city and cure them, which was a pita. I also didn’t want the enemies to respawn. But when I rested in Chapter 6 it didn’t seem to matter – no one got sick that night and the enemies were respawning on their own, anyway. Something they didn’t do at least up to Chapter 4.
The plot was good with a lot of options and hard decisions at key points. I’m sad that I made what turned out to be the wrong choice with one of the Pillars and the district went to shit, but at least it didn’t go all the way to chaos.
I missed about 1/4 of the NPC hints in the game and there were plenty of locked doors I never opened, which is frustrating. I’m assuming I would have had to kill NPCs to gain access to those hints and doors.
Certainly the best Vampire game since Bloodlines. Bloodlines is tough to play by today’s standards, though, even with the community patch. It’s a bit long in the tooth.