That study found 3 deaths out of 17 people with the mutation, compared to 7 out of 141 people without.
It’s a significant difference, but just barely. Given the small sample size, the actual added risk may be very small, or extremely high. “Fourfold higher” is a split-the-difference estimate that raises more questions then it answers. I put very little faith in that figure, and therefore it is hard to make a confident answer as to whether the mutation helps or hurts.
Like I said, a drug that blocked CCR5 would certainly merit further testing. Even in places like China.
Lo and behold, a CCR5 inhibitor already exists! And not only that, it is already FDA approved and is sold by Pfizer under the brand name Selzentry.
An old D&D buddy of mine built a pretty nice axe throwing, uh…range? in his backyard a few years ago. As far as I know, it’s still the centerpiece of his house parties to this day, though we kinda drifted apart.
It’s actually* pretty fun, but at $20/person/hour, something I’d just recommend trying once. Glad I did it, but not worth the money to do regularly.
They have pretty reasonable and thorough safety rules, though I’ve gotta say enforcement can be a problem. I’ve been a handful of times just as a non-paying, non-playing member of other groups, and on at least one occasion there was another group just being complete assholes**. Throwing two axes at once, throwing a second axe while there was already one stuck in the board, doing all sorts of stuff you’re specifically told not to do. They couldn’t stop trying to out-macho each other; they were just generally full of themselves, loud, and obnoxious. Not uncommon behavior out in the world (and especially in any kind of competitive atmosphere you could amp up with alcohol), but when it’s people throwing axes as hard as they can in the same room as me? Not ashamed to say I attempted to narc them out to the staff, which only resulted in a weak scolding.
So, legitimately fun event, overpriced in my area, but ultimately “What Could Possibly Go Wrong?” is still an open question and depends on how safely the establishment is run.