Okay, this game changes so much with resources. People were saying don’t turtle, but you had no choice before because you didn’t have the resources to, say, build a half-dozen maintenance hubs to cover a sprawling base.
Your base shouldn’t be a dense megapolis. It should have some central cores, but it should constantly be reaching out in all directions, like tendrils. Build a ton of worker nodes. In my first games, I limited my worker nodes to about 10 because, again, you simply didn’t have the resources to build the nodes, then build the workers, then replace the workers. And then I ended up wondering why the hell everything was so inefficient. In my current game, I’m over 40+ workers and I’m only operating in two sectors. Hey, the game is fun when it actually works correctly!
Constantly exploit resources and build resource scanners along the way. You’ll build the scanners at your main base at first, but the further they are from the target they are scanning, the longer it takes. I dissembled all my base scanners and build them along my network as I probe into virgin territory. Even on long stretches the network you need small nodes where there are power and maintenance hubs, so that’s a good place to put a scanner.
When you’re tasked with opening up new sectors, put colonies and research stations there. Make sure to build storage facilities there so you don’t have to schlep EVERYTHING from your main base halfway across Mars when you need to build something. You can set minimum levels for materials; the AI will shuttle over materials continually so it’s at the storage facility when you need it. Upgrade your roads linking your main base to your far-flung outposts to make this constant transfer as efficient as possible.
Even with the patch they don’t make Uranium easy to find. I had to probe outwards quite a bit before I find a single vein. (Thankfully, it was 2,000+). They do gate your Uranium levels by making it slow to extract, though.
This is what my current Mars effort looks like. The uranium is the lower left. The scanners detected it and I made a right turn and built a road there immediately.